Chapter·BiostatisticsOdds ratio vs. relative risk

Definition and calculation of odds ratioDownloads

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1

You have been asked to quantify the relative risk of developing bacterial meningitis following exposure to a patient with active disease. You analyze 200 patients in total, half of which are controls. In the trial arm, 30% of exposed patients ultimately contracted bacterial meningitis. In the unexposed group, only 1% contracted the disease. Which of the following is the relative risk due to disease exposure?

A(30 * 99) / (70 * 1)

B[30 / (30 + 70)] / [1 / (1 + 99)]

C[70 / (30 + 70)] / [99 / (1 + 99)]

D[[1 / (1 + 99)] / [30 / (30 + 70)]]

E(70 * 1) / (30 * 99)

2

Group of 100 medical students took an end of the year exam. The mean score on the exam was 70%, with a standard deviation of 25%. The professor states that a student's score must be within the 95% confidence interval of the mean to pass the exam. Which of the following is the minimum score a student can have to pass the exam?

A45%

B63.75%

C67.5%

D20%

E65%

3

A medical research study is evaluating an investigational novel drug (medication 1) as compared with standard therapy (medication 2) in patients presenting to the emergency department with myocardial infarction (MI). The study enrolled a total of 3,000 subjects, 1,500 in each study arm. Follow-up was conducted at 45 days post-MI. The following are the results of the trial: Endpoints Medication 1 Medication 2 P-Value Primary: death from cardiac causes 134 210 0.03 Secondary: hyperkalemia 57 70 0.4 What is the relative risk of death from a cardiac cause, expressed as a percentage? (Round to the nearest whole number.)

A64%

B42%

C72%

D36%

E57%

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