A 57-year-old man calls his primary care physician to discuss the results of his annual laboratory exams. The results show that he has dramatically decreased levels of high-density lipoprotein (HDL) and mildly increased levels of low-density lipoprotein (LDL). The physician says that the HDL levels are of primary concern so he is started on the lipid level modifying drug that most effectively increases serum HDL levels. Which of the following is the most likely a side effect of this medication that the patient should be informed about?
AHepatotoxicity
BGallstones
CFlushing
DMalabsorption
EMyalgia
A 48-year-old man with a history of diabetes mellitus presents to his primary care physician with lethargy, joint pain, and impotence. Lab evaluation is notable for a ferritin of 1400 ug/L (nl <300 ug/L), increased total iron, increased transferrin saturation, and decreased total iron binding capacity. All of the following are true regarding this patient's condition EXCEPT:
AIt is associated with an increased risk for hepatocellular carcinoma
BIt may improve with serial phlebotomy
CIt may lead to a decline in cardiac function
DIt results in skin bronzing
EIt may improve with calcium chelators
A previously healthy 44-year-old man comes to his physician because of frequent urination and increased thirst for several weeks. Physical examination shows darkened skin and a firm mass in the right upper quadrant. His blood glucose is 220 mg/dL. A photomicrograph of a specimen obtained on liver biopsy is shown. Which of the following best describes the pathogenesis of the disease process in this patient?
ADefective serum copper transportation
BDefective transferrin receptor binding
CAbsence of a serine protease inhibitor
DUpregulation of erythropoietin production
EAbsence of β-globin synthesis
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