Chapter·AnatomyCorticospinal tracts

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1

A neurology resident sees a stroke patient on the wards. This 57-year-old man presented to the emergency department after sudden paralysis of his right side. He was started on tissue plasminogen activator within 4 hours, as his wife noticed the symptoms and immediately called 911. When the resident asks the patient how he is doing, he replies by saying that his apartment is on Main St. He does not seem to appropriately answer the questions being asked, but rather speaks off topic. He is able to repeat the word "fan." His consciousness is intact, and his muscle tone and reflexes are normal. Upon striking the lateral part of his sole, his big toe extends upward and the other toes fan out. Which of the following is the area most likely affected in his condition?

ACaudate nucleus

BBroca’s area

CArcuate fasciculus

DTemporal lobe

ECuneus gyrus

2

A 72-year-old man with longstanding history of diabetes mellitus and hypertension presents to the emergency department with sudden-onset numbness. On your neurological exam, you note that he has loss of sensation on the left side of his face, arm, and leg. His motor strength exam is normal, as are his cranial nerves. Which of the following is the most likely explanation for his presentation?

AMiddle cerebral artery stroke

BThalamic stroke

CConversion disorder

DAnterior cerebral artery stroke

EBasilar artery stroke

3

A 35-year-old man who suffered a motor vehicle accident 3 months ago presents to the office for a neurological evaluation. He has no significant past medical history and takes no current medications. He has a family history of coronary artery disease in his father and Alzheimer’s disease in his mother. On physical examination, his blood pressure is 110/60 mm Hg, the pulse is 85/min, the temperature is 37.0°C (98.6°F), and the respiratory rate is 20/min. Neurological examination is suggestive of a lesion in the anterior spinal artery that affects the anterior two-thirds of the spinal cord, which is later confirmed with angiography. Which of the following exam findings would have suggested this diagnosis?

ALoss of vibratory sense below the level of the lesion

BLoss of pain and temperature sensation above the level of the lesion

CNegative plantar extensor response in his lower limbs

DFlaccid paralysis on the right side

EPreserved pressure sensation

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