A 4-week-old infant is brought to the emergency department by his parents with violent vomiting. It started about 3 days ago and has slowly gotten worse. He vomits after most feedings but seems to keep some formula down. His mother notes that he is eager to feed between episodes and seems to be putting on weight. Other than an uncomplicated course of chlamydia conjunctivitis, the infant has been healthy. He was born at 39 weeks gestation via spontaneous vaginal delivery. He is up to date on all vaccines and is meeting all developmental milestones. The physical exam is significant for a palpable mass in the right upper quadrant. What is the first-line confirmatory diagnostic test and associated finding?
AAbdominal ultrasound; elongated pyloric channel and muscle hypertrophy
BBarium upper GI series; GE junction and portion of the stomach in thorax
CAir enema; filling defect and coil spring sign
DBarium upper GI series; bird beak sign and corkscrewing
EAbdominal X-ray; ‘double bubble’ sign
A research team is studying certain congenital anomalies of the respiratory tract. The method consists of marking a certain germinal layer with an isotope, following its development stages in chicken embryos, and finally analyzing the specimen. A given specimen of tissue is presented in the exhibit. Which of the following germinal structures most likely gave rise to the epithelial lining of this specimen?
AEctoderm
BNeural crest
CMesoderm
DEndoderm
ESurface ectoderm
A 52-year-old man comes to the physician because of a 3-month history of upper abdominal pain and nausea that occurs about 3 hours after eating and at night. These symptoms improve with eating. After eating, he often has a feeling of fullness and bloating. He has had several episodes of dark stools over the past month. He has smoked one pack of cigarettes daily for 40 years and drinks 2 alcoholic beverages daily. He takes no medications. His temperature is 36.4°C (97.5°F), pulse is 80/min, and blood pressure is 110/70 mm Hg. Abdominal examination shows epigastric tenderness with no guarding or rebound. Bowel sounds are normal. Which of the following treatments is most appropriate to prevent further complications of the disease in this patient?
AIntravenous vitamin B12 supplementation
BTruncal vagotomy
CAmoxicillin, clarithromycin, and omeprazole
DFundoplication, hiatoplasty, and gastropexy
EDistal gastrectomy with gastroduodenostomy
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