An excisional biopsy is performed and the diagnosis of superficial spreading melanoma is confirmed. The lesion is 1.1 mm thick. Which of the following is the most appropriate next step in management?
ASurgical excision with 0.5-1 cm safety margins only
BSurgical excision with 1 cm safety margins only
CSurgical excision with 1-2 cm safety margins only
DSurgical excision with 0.5-1 cm safety margins and sentinel lymph node study
ESurgical excision with 1-2 cm safety margins and sentinel lymph node study
A 64-year-old woman presents to the surgical oncology clinic as a new patient for evaluation of recently diagnosed breast cancer. She has a medical history of type 2 diabetes mellitus for which she takes metformin. Her surgical history is a total knee arthroplasty 7 years ago. Her family history is insignificant. Physical examination is notable for an irregular nodule near the surface of her right breast. Her primary concern today is which surgical approach will be chosen to remove her breast cancer. Which of the following procedures involves the removal of a portion of a breast?
AArthroplasty
BLumpectomy
CVasectomy
DMastectomy
ELaminectomy
A 70-year-old man comes to the physician because of right-sided back pain, red urine, and weight loss for the last 4 months. He has smoked one pack of cigarettes daily for 40 years. A CT scan of the abdomen shows a large right-sided renal mass. Biopsy of the mass shows polygonal clear cells filled with lipids. Which of the following features is necessary to determine the tumor grade in this patient?
AInvasion of surrounding structures
BResponse to chemotherapy
CNuclear pleomorphism and nucleolar prominence
DInvolvement of regional lymph nodes
ESize of malignant proliferation
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