A 33-year-old woman comes to the emergency department because of a 1-hour history of severe pelvic pain and nausea. She was diagnosed with a follicular cyst in the left ovary 3 months ago. The cyst was found incidentally during a fertility evaluation. A pelvic ultrasound with Doppler flow shows an enlarged, edematous left ovary with no blood flow. Laparoscopic evaluation shows necrosis of the left ovary, and a left oophorectomy is performed. During the procedure, blunt dissection of the left infundibulopelvic ligament is performed. Which of the following structures is most at risk of injury during this step of the surgery?
ABladder trigone
BUterine artery
CKidney
DUreter
A 47-year-old woman presents with abnormal vaginal bleeding. She reports that she has had heavy, irregular periods for the past 6 months. Her periods, which normally occur every 28 days, are sometimes now only 2-3 weeks apart, last 7-10 days, and has spotting in between menses. Additionally, her breasts feel enlarged and tender. She denies abdominal pain, dysuria, dyspareunia, constipation, or abnormal vaginal discharge. The patient has a history of depression and hyperlipidemia. She takes fluoxetine and atorvastatin. She is a widow and has 2 healthy children. She works as an accountant. The patient says she drinks a half bottle of wine every night to help her calm down after work and to help her sleep. She denies tobacco or illicit drug use. She is not currently sexually active. Physical examination reveals spider angiomata and mild ascites. The left ovary is palpable but non-tender. A thickened endometrial stripe and a left ovarian mass are noted on ultrasound. A mammogram, chest radiograph, and CT abdomen/pelvis are pending. Which of the following tumor markers is associated with the patient’s most likely diagnosis?
AAlpha-fetoprotein
BEstrogen
CTestosterone
DCarcinoembryonic antigen
ECancer antigen-125
Patient 1 – A 26-year-old woman presents to her primary care physician for an annual exam. She currently does not have any acute concerns and says her health has been generally well. Medical history is significant for asthma, which is managed with an albuterol inhaler. Her last pap smear was unremarkable. She is currently sexually active with one male and consistently uses condoms. She occasionally smokes marijuana and drinks wine once per week. Her mother recently passed away from advanced ovarian cancer. Her sister is 37-years-old and was recently diagnosed with breast cancer and ovarian cancer. Physical examination is remarkable for a mildly anxious woman. Patient 2 – A 27-year-old woman presents to her primary care physician for an annual exam. She says that she would like to be screened for breast cancer since two of her close friends were recently diagnosed. She noticed she has a small and mobile mass on her left breast, which increases in size and becomes tender around her time of menses. Family history is remarkable for hypertension in the father. The physical exam is significant for a small, well-defined, and mobile mass on her left breast that is not tender to palpation. Which of the following is the best next step in management for patient 1 and 2?
APatient 1 – Breast ultrasound. Patient 2 – Return in 3 months for a clinical breast exam
BPatient 1 – Reassurance. Patient 2 – Breast ultrasound
CPatient 1 – CA-125 testing. Patient 2 – BRCA testing
DPatient 1 – BRCA testing. Patient 2 – Breast ultrasound
EPatient 1 – Breast and ovarian ultrasound. Patient 2 – Mammography
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