A 42-year-old man is discovered unconscious by local police while patrolling in a park. He is unresponsive to stimulation. Syringes were found scattered around him. His heart rate is 70/min and respiratory rate is 6/min. Physical examination reveals a disheveled man with track marks on both arms. His glasgow coma scale is 8. Pupillary examination reveals miosis. An ambulance is called and a reversing agent is administered. Which of the following is most accurate regarding the reversal agent most likely administered to this patient?
AWorks on dopamine receptors
BHas a short half-life
CCan be given per oral
DResults in acute withdrawal
EIs a non-competitive inhibitor
A 44-year-old man presents to the clinic worried about his risk for bladder cancer. His best friend who worked with him as a painter for the past 20-years died recently after being diagnosed with transitional cell carcinoma. He is worried that their long and heavy cigarette smoking history might have contributed to his death. He also reports that he has been feeling down since his friend's death 2 months ago and has not been eating or sleeping as usual. He took time off from work but now is running past due on some of his bills. He feels like he is moving a lot slower than usual. He would like to stop smoking but feels like it's impossible with just his willpower. What side-effect is most likely if this patient were started on his appropriate pharmacotherapy?
ACan decrease seizure threshold
BCan treat overdose with sodium bicarbonate
CCan cause restlessness at initiation or termination
DCan cause sedation and weight gain
ECan worsen uncontrolled hypertension
A 27-year-old homeless man presents to the emergency department with abdominal pain and vomiting. He has a known history of intravenous drug use and has been admitted to the hospital several times before. On physical examination his temperature is 99°F (37.2°C), blood pressure is 130/85 mmHg, pulse is 90/min, respirations are 19/min, and pulse oximetry is 99% on room air. The patient is in obvious discomfort. There is increased salivation and lacrimation. Pupils are reactive to light and 5 mm bilaterally. Cardiopulmonary exam is unremarkable. There is diffuse abdominal tenderness to palpation with no rebound or guarding. Which of the following interventions would have prevented this patient’s current condition?
ANaltrexone
BBuprenorphine
CLorazepam
DNaloxone
EBupropion
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