Chapter·PsychiatryGenetic and Metabolic Disorders

Inborn Errors of MetabolismDownloads

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1

An infant presents with vomiting after feeding. Benedict's test was positive for a non-glucose reducing substance. What is the most likely diagnosis?

AGalactosemia due to GAL-1-P Uridyl Transferase enzyme deficiency

BFructosuria due to Fructokinase deficiency

CHereditary fructose intolerance due to Aldolase B deficiency

DPrimary lactose intolerance

EGlycogen storage disease due to Glucose-6-phosphatase deficiency

2

Congenital lactic acidosis is primarily due to a defect in which enzyme?

ABranched chain alpha-ketoacid dehydrogenase

BIsocitrate dehydrogenase (IDH)

CTransketolase

DPyruvate dehydrogenase

3

Tay-Sachs disease is due to a deficiency of which enzyme?

AHexosaminidase B

Bα-galactosidase

CHexosaminidase A

DSphingomyelinase

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