A healthy 30-year-old female has a measured creatinine clearance of 100 mL/min. She has a filtration fraction (FF) of 25%. Serum analysis reveals a creatinine level of 0.9 mg/dL and an elevated hematocrit of 0.6. Which of the following is the best estimate of this patient’s renal blood flow?
A1.2 L/min
B600 mL/min
C800 mL/min
D400 mL/min
E1.0 L/min
A 64-year-old African American female comes to the physician's office for a routine check-up. The patient's past medical history is significant for hypertension, diabetes, and osteoarthritis in her right knee. Her medications include metformin, glimepiride, lisinopril, metoprolol, hydrochlorothiazide, and ibuprofen as needed. Her only complaint is an unremitting cough that started about 3 weeks ago and she has noticed some swelling around her mouth. The drug most likely responsible for her recent symptoms causes its primary renal hemodynamic effect on which part of the kidney?
ACollecting duct
BDistal convoluted tubule
CJuxtaglomerular cells
DEfferent arteriole
EAfferent arteriole
On cardiology service rounds, your team sees a patient admitted with an acute congestive heart failure exacerbation. In congestive heart failure, decreased cardiac function leads to decreased renal perfusion, which eventually leads to excess volume retention. To test your knowledge of physiology, your attending asks you which segment of the nephron is responsible for the majority of water absorption. Which of the following is a correct pairing of the segment of the nephron that reabsorbs the majority of all filtered water with the means by which that segment absorbs water?
ADistal convoluted tubule via passive diffusion following ion reabsorption
BDistal convoluted tubule via aquaporin channels
CThick ascending loop of Henle via passive diffusion following ion reabsorption
DProximal convoluted tubule via passive diffusion following ion reabsorption
ECollecting duct via aquaporin channels
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