A healthy 30-year-old female has a measured creatinine clearance of 100 mL/min. She has a filtration fraction (FF) of 25%. Serum analysis reveals a creatinine level of 0.9 mg/dL and an elevated hematocrit of 0.6. Which of the following is the best estimate of this patient’s renal blood flow?
A1.2 L/min
B600 mL/min
C800 mL/min
D400 mL/min
E1.0 L/min
A 39-year-old woman is brought to the emergency department in a semi-unconscious state by her neighbor who saw her lose consciousness. There was no apparent injury on the primary survey. She is not currently taking any medications. She has had loose stools for the past 3 days and a decreased frequency of urination. No further history could be obtained. The vital signs include: blood pressure 94/62 mm Hg, temperature 36.7°C (98.0°F), pulse 105/min, and respiratory rate 10/min. The skin appears dry. Routine basic metabolic panel, urine analysis, urine osmolality, and urine electrolytes are pending. Which of the following lab abnormalities would be expected in this patient?
ASerum blood urea nitrogen/creatinine (BUN/Cr) > 20
BUrine osmolality < 350 mOsm/kg
CFractional excretion of sodium (FENa) > 2%
DUrine Na+ > 40 mEq/L
ESerum creatinine < 1 mg/dL
A laboratory technician processes basic metabolic panels for two patients. Patient A is 18 years old and patient B is 83 years old. Neither patient takes any medications regularly. Serum laboratory studies show: Patient A Patient B Na+ (mEq/L) 145 141 K+ (mEq/L) 3.9 4.4 Cl- (mEq/L) 103 109 HCO3- (mEq/L) 22 21 BUN (mg/dL) 18 12 Cr (mg/dL) 0.8 1.2 Glucose (mg/dL) 105 98 Which of the following most likely accounts for the difference in creatinine seen between these two patients?
AVolume depletion
BLow body mass index
CInsulin resistance
DNormal aging
EHigh serum aldosterone levels
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