Chapter·PhysiologyGas exchange

Chloride shift mechanismDownloads

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1

During a clinical study examining the diffusion of gas between the alveolar compartment and the pulmonary capillary blood, men between the ages of 20 and 50 years are evaluated while they hold a sitting position. After inhaling a water-soluble gas that rapidly combines with hemoglobin, the concentration of the gas in the participant's exhaled air is measured and the diffusion capacity is calculated. Assuming that the concentration of the inhaled gas remains the same, which of the following is most likely to increase the flow of the gas across the alveolar membrane?

ADeep exhalation

BEntering a cold chamber

CTreadmill exercise

DStanding straight

EAssuming a hunched position

2

A 58-year-old man presents to the emergency department with a chief complaint of ringing in his ears that started several hours previously that has progressed to confusion. The patient denies any history of medical problems except for bilateral knee arthritis. He was recently seen by an orthopedic surgeon to evaluate his bilateral knee arthritis but has opted to not undergo knee replacement and prefers medical management. His wife noted that prior to them going on a hike today, he seemed confused and not himself. They decided to stay home, and roughly 14 hours later, he was no longer making any sense. Physical exam is notable for a confused man. The patient's vitals are being performed and his labs are being drawn. Which of the following is most likely to be seen on blood gas analysis?

ApH: 7.30, PaCO2: 15 mmHg, HCO3-: 16 mEq/L

BpH: 7.37, PaCO2: 41 mmHg, HCO3-: 12 mEq/L

CpH: 7.41, PaCO2: 65 mmHg, HCO3-: 34 mEq/L

DpH: 7.47, PaCO2: 11 mmHg, HCO3-: 24 mEq/L

EpH: 7.31, PaCO2: 31 mmHg, HCO3-: 15 mEq/L

3

A 17-year-old female is brought to the emergency room by her parents shortly after a suicide attempt by aspirin overdose. Which of the following acid/base changes will occur FIRST in this patient?

AMetabolic alkalosis

BRespiratory acidosis

CAnion gap metabolic acidosis

DRespiratory alkalosis

ENon-anion gap metabolic acidosis

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