Which receptor type mediates the slow phase of synaptic transmission in autonomic ganglia?
AMuscarinic (M3)
BMuscarinic (M2)
CMuscarinic (M1)
DNicotinic (N2)
A 23-year-old woman presents to the emergency department with acute onset of shortness of breath, wheezing, and chest tightness. This is her 4th visit for these symptoms in the last 5 years. She tells you she recently ran out of her normal "controller" medication. Concerned for an asthma exacerbation, you begin therapy with a short-acting beta2-agonist. What is the expected cellular response to your therapy?
AGs protein coupled receptor activates adenylyl cyclase and increases intracellular cAMP
BGq protein coupled receptor activates phospholipase C and increases intracellular calcium
CGq protein coupled receptor activates adenylyl cyclase and increases intracellular cAMP
DGs protein coupled receptor activates phospholipase C and increases intracellular calcium
EGi protein coupled receptor inhibits adenylyl cyclase and decreases cAMP
A 60-year-old man presents to the office for a scheduled follow-up visit. He has had hypertension for the past 30 years and his current anti-hypertensive medications include lisinopril (40 mg/day) and hydrochlorothiazide (50 mg/day). He follows most of the lifestyle modifications recommended by his physician, but is concerned about his occasional occipital headaches in the morning. His blood pressure is 160/98 mm Hg. The physician adds another drug to his regimen that acts centrally as an α2-adrenergic agonist. Which of the following second messengers is involved in the mechanism of action of this new drug?
ACalcium ions
BInositol triphosphate
CCyclic guanosine monophosphate
DCyclic adenosine monophosphate
EDiacylglycerol
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