Which receptor type mediates the slow phase of synaptic transmission in autonomic ganglia?
AMuscarinic (M3)
BMuscarinic (M2)
CMuscarinic (M1)
DNicotinic (N2)
A 32-year-old farmer is brought to the emergency department by his wife. The patient was reportedly anxious, sweaty, and complaining of a headache and chest tightness before losing consciousness on route to the hospital. Which of the following is mechanistically responsible for this patient's symptoms?
AReversible inhibition of acetylcholinesterase
BCompetitive inhibition of acetylcholine at post-junctional effector sites
CBinding of acetylcholine agonists to post-junctional receptors
DIrreversible inhibition of acetylcholinesterase
EInhibition of presynaptic exocytosis of acetylcholine vesicles
A scientist is trying to design a drug to modulate cellular metabolism in the treatment of obesity. Specifically, he is interested in understanding how fats are processed in adipocytes in response to different energy states. His target is a protein within these cells that catalyzes catabolism of an energy source. The products of this reaction are subsequently used in gluconeogenesis or β-oxidation. Which of the following is true of the most likely protein that is being studied by this scientist?
AIt is stimulated by epinephrine
BIt is inhibited by glucagon
CIt is inhibited by acetylcholine
DIt is inhibited by cortisol
EIt is stimulated by insulin
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