Chapter·PharmacologyAutonomic/CV Drugs

Class II antiarrhythmics (beta blockers)Downloads

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1

A 23-year-old woman presents to the emergency department with acute onset of shortness of breath, wheezing, and chest tightness. This is her 4th visit for these symptoms in the last 5 years. She tells you she recently ran out of her normal "controller" medication. Concerned for an asthma exacerbation, you begin therapy with a short-acting beta2-agonist. What is the expected cellular response to your therapy?

AGs protein coupled receptor activates adenylyl cyclase and increases intracellular cAMP

BGq protein coupled receptor activates phospholipase C and increases intracellular calcium

CGq protein coupled receptor activates adenylyl cyclase and increases intracellular cAMP

DGs protein coupled receptor activates phospholipase C and increases intracellular calcium

EGi protein coupled receptor inhibits adenylyl cyclase and decreases cAMP

2

A 39-year-old woman is brought to the emergency department 30 minutes after her husband found her unconscious on the living room floor. She does not report having experienced light-headedness, nausea, sweating, or visual disturbance before losing consciousness. Three weeks ago, she was diagnosed with open-angle glaucoma and began treatment with an antiglaucoma drug in the form of eye drops. She last used the eye drops 1 hour ago. Examination shows pupils of normal size that are reactive to light. An ECG shows sinus bradycardia. This patient is most likely undergoing treatment with which of the following drugs?

ABrimonidine

BDorzolamide

CLatanoprost

DPilocarpine

ETimolol

3

A 25-year-old female presents to the emergency room with a heart rate of 32 BPM and a blood pressure of 80/40. She was found by emergency medical services with an empty bottle of propranolol that was taken from her grandmother. Her vital signs do not improve despite IV fluids and oxygen. Which of the following is a first line treatment for overdose?

AHemodialysis

BAdenosine

CAtropine

DVagal maneuvers

EGlucagon

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