A 57-year-old man comes to the physician for a follow-up visit. Serum studies show: AST 134 U/L ALT 152 U/L Hepatitis B surface antigen Positive A photomicrograph of the microscopic findings of a liver biopsy is shown. These biopsy findings are most characteristic of which of the following types of inflammatory reactions?
AMalignant transformation
BGranulomatous inflammation
CChronic inflammation
DAcute inflammation
EIschemic necrosis
A 38-year-old woman comes to the physician because of a 3-month history of moderate abdominal pain that is unresponsive to medication. She has a history of two spontaneous abortions at 11 and 12 weeks' gestation. Ultrasound examination of the abdomen shows normal liver parenchyma, a dilated portal vein, and splenic enlargement. Upper endoscopy shows dilated submucosal veins in the lower esophagus. Further evaluation of this patient is most likely to show which of the following findings?
AIncreased serum bilirubin levels
BIncreased prothrombin time
CThrombocytopenia
DHepatic venous congestion
ECouncilman bodies
A 57-year-old man presents with fever and yellow discoloration of the skin for the past 4 days. He denies any recent weight loss or changes in urine or stool color. His past medical history is unremarkable. He admits to drinking about 130 g/day of alcohol and says he has been doing so for the past 25 years. His wife who is accompanying him during this visit adds that once her husband drank 15 cans of beer at a funeral. The patient also reports a 10-pack-year smoking history. His vital signs include: pulse 98/min, respiratory rate 13/min, temperature 38.2°C (100.8°F) and blood pressure 120/90 mm Hg. On physical examination, the patient appears jaundiced and is ill-appearing. Sclera is icteric. Abdominal examination reveals tenderness to palpation in the right upper quadrant with no rebound or guarding. Percussion reveals significant hepatomegaly extending 3 cm below the right costal margin. Laboratory studies are significant for the following: Sodium 135 mEq/L Potassium 3.5 mEq/L ALT 240 U/L AST 500 U/L A liver biopsy is obtained but the results are pending. Which of the following would most likely be seen in this patient's biopsy?
ASteatosis alone
BHürthle cells
C'Florid' bile duct lesion
DGaucher cells
EMallory-Denk bodies
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