Chapter·PathologyRenal pathology

Nephrotic syndrome disordersDownloads

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Sample Questions

1

A 43-year-old man comes to the physician for a 1-week history of swelling around his eyes and decreased urination. His pulse is 87/min, and blood pressure is 152/95 mm Hg. Physical examination shows 1+ periorbital and pretibial edema. Serum studies show a urea nitrogen concentration of 21 mg/dL and a creatinine concentration of 1.4 mg/dL. Urinalysis shows 3+ blood and 1+ protein. Further evaluation of this patient is most likely to show which of the following?

AUrinary rhomboid crystals

BRenal interstitial inflammation

CHypoalbuminemia

DDetached renal tubular epithelial cells

ERed blood cell casts

2

A 44-year-old man comes to the physician because of a 2-week history of lower extremity swelling and frothy urine. He has a history of chronic hepatitis C infection. Physical examination shows 3+ pitting edema of the lower legs and ankles. Further evaluation of this patient is most likely to show which of the following?

ADecreased cholesterol

BDecreased blood urea nitrogen

CIncreased antithrombin III

DDecreased cystatin C

EIncreased lipoproteins

3

A 70-year-old man with a long-standing history of diabetes mellitus type 2 and hypertension presents with complaints of constant wrist and shoulder pain. Currently, the patient undergoes hemodialysis 2 to 3 times a week and is on the transplant list for a kidney. The patient denies any recent traumas. Which of the following proteins is likely to be increased in his plasma, causing the patient’s late complaints?

AAmyloid precursor protein

BAmyloid A (AA)

Cβ2-microglobulin

DTransthyretin (TTR)

EIg light chains

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