A 48-year-old Caucasian male suffering from ischemic heart disease is placed on a heart transplant list. Months later, he receives a heart from a matched donor. During an endomyocardial biopsy performed 3 weeks later, there is damage consistent with acute graft rejection. What is most likely evident on the endomyocardial biopsy?
AGranuloma
BAtherosclerosis
CLymphocytic infiltrate
DTissue necrosis
EFibrosis
A 31-year-old female receives a kidney transplant for autosomal dominant polycystic kidney disease (ADPKD). Three weeks later, the patient experiences acute, T-cell mediated rejection of the allograft and is given sirolimus. Which of the following are side effects of this medication?
ANephrotoxicity, hypertension
BHyperlipidemia, thrombocytopenia
CNephrotoxicity, gingival hyperplasia
DPancreatitis
ECytokine release syndrome, hypersensitivity reaction
A 10-year-old boy is presented to the hospital for a kidney transplant. In the operating room, the surgeon connects an allograft kidney renal artery to the aorta, and after a few moments, the kidney becomes cyanotic, edematous, and dusky with mottling. Which of the following in the recipient’s serum is responsible for this rejection?
AMacrophages
BCD4+ T cells
CIgA
DCD8+ T cells
EIgG
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