A 14-year-old girl presents with pain in the right lower quadrant of her abdomen. She describes the pain as sudden, severe, colicky, and associated with nausea and vomiting. Physical exam reveals tachycardia and severe tenderness to palpation with rebound in the right iliac region. Emergency laparotomy is performed which reveals an inflamed appendix. A presurgical blood cell count shows an increase in the number of cells having a multilobed nucleus and multiple cytoplasmic granules as shown in the image below. Which of the following is the main function of these cells?
ABlood clotting
BTransplant rejection
CAllergic reaction
DPhagocytosis
EAntigen presentation
A researcher is studying the interactions between foreign antigens and human immune cells. She has isolated a line of lymphocytes that is known to bind antigen-presenting cells. From this cell line, she has isolated a cell surface protein that binds to class I major histocompatibility complex molecules. The continued activation, proliferation and survival of this specific cell line requires which of the following signaling molecules?
AInterleukin 1
BInterleukin 4
CInterleukin 2
DInterleukin 8
EInterleukin 6
A 32-year-old man who recently emigrated from Somalia comes to the physician because of a 4-week history of fever, cough, and chest pain. He has had a 5-kg (11-lb) weight loss over the last 3 months despite no changes in appetite. His temperature is 38.1°C (100.6°F). Physical examination shows enlarged cervical lymph nodes. The lungs are clear to auscultation. The results of an interferon-γ release assay are positive. An x-ray of the chest shows bilateral mediastinal lymphadenopathy. A transbronchial needle aspiration biopsy of a mediastinal lymph node is performed; a photomicrograph of the specimen is shown. The structure indicated by the arrow is most likely comprised of which of the following types of cells?
ANatural killer cells
BB cells
CFibroblasts
DNeutrophils
EMacrophages
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