Chapter·PathologyGeneral Pathology

Laboratory techniques in pathologyDownloads

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Sample Questions

1

An investigator studying the molecular characteristics of various malignant cell lines collects tissue samples from several families with a known mutation in the TP53 tumor suppressor gene. Immunohistochemical testing performed on one of the cell samples stains positive for desmin. This sample was most likely obtained from which of the following neoplasms?

ASquamous cell carcinoma

BRhabdomyosarcoma

CProstate cancer

DEndometrial carcinoma

EMelanoma

2

During an experiment, the immunophenotypes of different cells in a sample are determined. The cells are labeled with fluorescent antibodies specific to surface proteins, and a laser is then focused on the samples. The intensity of fluorescence created by the laser beam is then plotted on a scatter plot. The result shows most of the cells in the sample to be positive for CD8 surface protein. Which of the following cell types is most likely represented in this sample?

AMature cytotoxic T lymphocytes

BActivated regulatory T lymphocytes

CInactive B lymphocytes

DDendritic cells

EMature helper T lymphocytes

3

A 16-year-old boy presents to the emergency department after a skateboarding accident. He fell on a broken bottle and received a 4 cm wound on the dorsal aspect of his left hand. His vitals are stable and he was evaluated by the surgeon on call who determined that suturing was not required. After several weeks the wound has almost completely healed (see image). Which of the following is the correct description of this patient's wound before healing?

AIncised wound

BAbrasion

CLaceration

DAvulsion

EPuncture

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