A 3-year-old boy presents to the clinic for evaluation of leg pain. This has been persistent for the past 3 days and accompanied by difficulty walking. He has also had some erythema and ecchymoses in the periorbital region over the same time period. The vital signs are unremarkable. The physical exam notes the above findings, as well as some swelling of the upper part of the abdomen. The laboratory results are as follows: Erythrocyte count 3.3 million/mm3 Leukocyte count 3,000/mm3 Neutrophils 54% Eosinophils 1% Basophils 1% Lymphocytes 43% Monocytes 3% Platelet count 80,000/mm3 A magnetic resonance image (MRI) scan of the abdomen shows a mass of adrenal origin. Which of the following is the most likely cause of this patient's symptoms?
AHepatoblastoma
BRhabdomyosarcoma
CNeuroblastoma
DWilms tumor
ERetinoblastoma
A 35-year-old woman presents with increased anxiety and a reeling sensation. Her complaint started 30 minutes ago with increased sweating and palpitations and is gradually worsening. On examination, the blood pressure was found to be 194/114 mm Hg. She had normal blood pressure at the local pharmacy 5 days ago. She currently works as an event manager and her job involves a lot of stress. The family history is significant for thyroid carcinoma in her father. Which of the following is most likely in this person?
AIncreased urine metanephrines
BDecreased C-peptide
CDecreased hemoglobin
DDecreased TSH levels
EIncreased serum serotonin
A researcher is studying receptors that respond to epinephrine in the body and discovers a particular subset that is expressed in presynaptic adrenergic nerve terminals. She discovers that upon activation, these receptors will lead to decreased sympathetic nervous system activity. She then studies the intracellular second messenger changes that occur when this receptor is activated. She records these changes and begins searching for analogous receptor pathways. Which of the following receptors would cause the most similar set of intracellular second messenger changes?
AMuscarinic cholinoreceptors in the gastrointestinal tract
BGrowth hormone receptors in the musculoskeletal system
CVasopressin receptors in the kidney
DDopamine receptors in the brain
EAldosterone receptors in the kidney
+ 7 more in the PDF
Browse all chapters