Chapter·PathologyDermatopathology

Dermal tumors and proliferationsDownloads

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1

A 57-year-old post-menopausal woman comes to the physician because of intermittent, bloody post-coital vaginal discharge for the past month. She does not have pain with intercourse. Eleven years ago, she had LSIL on a routine Pap smear and testing for high-risk HPV strains was positive. Colposcopy showed CIN 1. She has not returned for follow-up Pap smears since then. She is sexually active with her husband only, and they do not use condoms. She has smoked half a pack of cigarettes per day for the past 25 years and does not drink alcohol. On speculum exam, a 1.4 cm, erythematous exophytic mass with ulceration is noted on the posterior wall of the upper third of the vagina. Which of the following is the most probable histopathology of this mass?

ABasal cell carcinoma

BMelanoma

CAdenocarcinoma

DSarcoma botryoides

ESquamous cell carcinoma

2

A 59-year-old man with chronic hepatitis C infection comes to the physician because of a 2-week history of ankle pain and nonpruritic skin lesions on his legs. He does not recall recent trauma or injury. He has not received treatment for hepatitis. Examination shows diffuse, violaceous lesions on both lower extremities. The lesions are 4–7 mm in size, slightly raised, and do not blanch with pressure. These skin lesions are best classified as which of the following?

AEcchymoses

BPetechiae

CHemangioma

DSpider angioma

EPurpura

3

A 6-year-old boy is brought to the physician by his parents because of right lower extremity weakness, worsening headaches, abdominal pain, dark urine, and a 5-kg (11-lb) weight loss for the past 2 months. His teachers report that he has not been paying attention in class and his grades have been worsening. He has a history of infantile seizures. Physical examination shows a palpable abdominal mass and left costovertebral angle tenderness. Neurological exam shows decreased strength of the right lower limb. He has several acne-like angiofibromas around the nose and cheeks. Further evaluation is most likely to show which of the following?

ASubependymal giant cell astrocytoma

BVestibular schwannoma

CPheochromocytoma

DLisch nodules

ERenal angiomyolipomas

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