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Viral hemorrhagic feversDownloads

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1

A 43-year-old male visits the emergency room around 4 weeks after getting bitten by a bat during a cave diving trip. After cleansing the wound with water, the patient reports that he felt well enough not to seek medical attention immediately following his trip. He does endorse feeling feverish in the past week but a new onset of photophobia and irritability led him to seek help today. What would the post-mortem pathology report show if the patient succumbs to this infection?

AHowell-Jolly bodies

BHeinz bodies

CPsammoma bodies

DPick bodies

ENegri bodies

2

A 25-year-old woman comes to the physician because of a 2-week history of episodic bleeding from the nose and gums and one episode of blood in her urine. She was treated with chloramphenicol 1 month ago for Rickettsia rickettsii infection. Her pulse is 130/min, respirations are 22/min, and blood pressure is 105/70 mm Hg. Examination shows mucosal pallor, scattered petechiae, and ecchymoses on the extremities. Laboratory studies show: Hemoglobin 6.3 g/dL Hematocrit 26% Leukocyte count 900/mm3 (30% neutrophils) Platelet count 50,000/mm3 The physician recommends a blood transfusion and informs her of the risks and benefits. Which of the following red blood cell preparations will most significantly reduce the risk of transfusion-related cytomegalovirus infection?

AWarming

BIrradiation

CCentrifugation

DWashing

ELeukoreduction

3

A previously healthy 25-year-old man comes to the physician because of a 4-day history of fever, joint and body pain, diffuse headache, and pain behind the eyes. This morning he noticed that his gums bled when he brushed his teeth. He returned from a backpacking trip to the Philippines 4 days ago. His temperature is 39.4°C (103.0°F). Physical examination shows a diffuse maculopapular rash. His leukocyte count is 3,200/mm3 and platelet count is 89,000/mm3. Further evaluation shows increased serum levels of a flavivirus. Which of the following is the most likely causal pathogen?

ADengue virus

BEbola virus

CChikungunya virus

DLassa virus

EHantavirus

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