A 23-year-old woman presents with vulvar ulcers and lymphadenopathy. Testing confirms primary HSV infection. Which of the following statements about HSV antibody development is correct?
AIgG appears immediately after infection
BIgG antibodies appear 2-3 weeks after infection and persist
CNo antibody response occurs
DIgM and IgG appear simultaneously at 6 weeks
If the genetic material were isolated and injected into the cytoplasm of a human cell, which of the following would produce viable, infectious virions?
ALassa fever virus
BRabies virus
CRhinovirus
DMumps virus
EInfluenza virus
A rapid diagnostic test has been developed amid a major avian influenza outbreak in Asia. The outbreak has reached epidemic levels with a very high attack rate. Epidemiologists are hoping to use the rapid diagnostic test to identify all exposed individuals and curb the rapid spread of disease by isolating patients with any evidence of exposure to the virus. The epidemiologists compared rapid diagnostic test results to seropositivity of viral antigen via PCR in 200 patients. The findings are represented in the following table: Test result PCR-confirmed avian influenza No avian influenza Positive rapid diagnostic test 95 2 Negative rapid diagnostic test 5 98 Which of the following characteristics of the rapid diagnostic test would be most useful for curbing the spread of the virus via containment?
APositive predictive value of 95/97
BSpecificity of 98/100
CSensitivity of 95/100
DNegative predictive value of 98/103
EAccuracy of 193/200
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