Chapter·MicrobiologyParasites/Fungi

Pneumocystis jiroveciiDownloads

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1

A 26-year-old man comes to the physician for a follow-up examination. He was diagnosed with HIV infection 2 weeks ago. His CD4+ T-lymphocyte count is 162/mm3 (N ≥ 500). An interferon-gamma release assay is negative. Prophylactic treatment against which of the following pathogens is most appropriate at this time?

ACytomegalovirus

BToxoplasma gondii

CMycobacterium tuberculosis

DAspergillus fumigatus

EPneumocystis jirovecii

2

A 50-year-old man with a remote history of intravenous drug use and a past medical history of AIDS presents to his primary care provider with several weeks of productive cough and a mild fever. He was in his normal state of health and slowly started to develop these symptoms. He is hoping to be prescribed an antibiotic so he can get back to “normal”. Family history is significant for cardiovascular disease and diabetes. He takes antiviral medication and a multivitamin daily. His heart rate is 90/min, respiratory rate is 19/min, blood pressure is 135/85 mm Hg, and temperature is 38.3°C (100.9°F). On physical examination, he looks uncomfortable. A chest examination reveals consolidation in the right lower lung. Chest radiography confirms right lower lobe pneumonia. Of the following options, which is the most likely cause of the patient’s pneumonia?

APulmonary sequestration

BPneumocystis pneumonia

CAspiration pneumonia

DCommunity-acquired pneumonia

EDisseminated cutaneous infection

3

A 33-year-old HIV-positive male is seen in clinic for follow-up care. When asked if he has been adhering to his HIV medications, the patient exclaims that he has been depressed, thus causing him to not take his medication for six months. His CD4+ count is now 33 cells/mm3. What medication(s) should he take in addition to his anti-retroviral therapy?

AAzithromycin and fluconazole

BAzithromycin, dapsone, and fluconazole

CDapsone

DFluconazole

EAzithromycin and trimethoprim-sulfamethoxazole

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