If the genetic material were isolated and injected into the cytoplasm of a human cell, which of the following would produce viable, infectious virions?
ALassa fever virus
BRabies virus
CRhinovirus
DMumps virus
EInfluenza virus
Six days after undergoing an elective hip replacement surgery, a 79-year-old man develops dysuria, flank pain, and fever. His temperature is 38.5°C (101.3°F). Examination shows marked tenderness in the right costovertebral area. Treatment with an antibiotic is begun, but his symptoms do not improve. Further evaluation shows that the causal organism produces an enzyme that inactivates the antibiotic via phosphorylation. An agent from which of the following classes of antibiotics was most likely administered?
AMacrolides
BTetracyclines
CAminoglycosides
DGlycopeptides
EFluoroquinolones
An 18-year old college freshman presents to his university clinic because he has not been feeling well for the past two weeks. He has had a persistent headache, occasional cough, and chills without rigors. The patient’s vital signs are normal and physical exam is unremarkable. His radiograph shows patchy interstitial lung infiltrates and he is diagnosed with atypical pneumonia. The patient is prescribed azithromycin and takes his medication as instructed. Despite adherence to his drug regimen, he returns to the clinic one week later because his symptoms have not improved. The organism responsible for this infection is likely resistant to azithromycin through which mechanism?
AMutation in topoisomerase II
BMethylation of ribosomal binding site
CPresence of a beta-lactamase
DDecreased binding to RNA polymerase
EInsertion of drug efflux pumps
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