A 32-year-old man comes to the physician because of a 1-week history of fever, weakness, diffuse abdominal pain, and multiple lumps on his body. He has recently returned to the USA from a 3-month agricultural internship in South America. Physical examination shows enlarged superficial cervical and inguinal lymph nodes. There is tender hepatomegaly. A photomicrograph of a liver biopsy sample after methenamine silver staining is shown. Which of the following is the most likely diagnosis?
AAspergillosis
BParacoccidioidomycosis
CBlastomycosis
DMalaria
EHistoplasmosis
A 58-year-old woman visits a physician because of fever, chills, dry cough, and a few enlarging masses on her cheeks and neck. Wart-like lesions are present on the nose as shown in the photograph. She reports that she visited the Mississippi area a few months before on a business trip. Her temperature is 38.1°C (100.6°F), the pulse is 80/min, and the blood pressure is 121/78 mm Hg. A fine needle aspirate of the lymph node is sent for pathological investigation. Culture growth shows white colonies on Sabouraud glucose agar (SGA). Which of the following is the most likely causal organism?
AHistoplasma capsulatum
BMalassezia furfur
CBlastomyces dermatitidis
DCoccidioides immitis
EAspergillus fumigatus
An investigator is studying growth patterns of various fungal pathogens. Incubation of an isolated fungus at 25°C shows branching hyphae with rosettes of conidia under light microscopy. After incubation at 37°C, microscopic examination of the same organism instead shows smooth, white colonies with rounded, elongated cells. Infection with the investigated pathogen is most likely to cause which of the following conditions?
APityriasis versicolor
BCandidiasis
CCryptococcosis
DSporotrichosis
ECoccidioidomycosis
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