A 44-year-old man comes to the physician because of a 3-week history of productive cough, fever, and lethargy. He also has several skin lesions over his body. His symptoms began 3 weeks after he returned from a camping trip in Kentucky. Three years ago, he underwent kidney transplantation for polycystic kidney disease. Current medications include sirolimus and prednisone. His temperature is 38°C (100.4°F). Diffuse crackles are heard over the lung fields. There are 4 white, verrucous skin patches over his chest and upper limbs. A photomicrograph of a skin biopsy specimen from one of the lesions is shown. Which of the following is the most likely diagnosis?
ACoccidioidomycosis
BMucormycosis
CBlastomycosis
DCryptococcosis
EHistoplasmosis
A 58-year-old woman visits a physician because of fever, chills, dry cough, and a few enlarging masses on her cheeks and neck. Wart-like lesions are present on the nose as shown in the photograph. She reports that she visited the Mississippi area a few months before on a business trip. Her temperature is 38.1°C (100.6°F), the pulse is 80/min, and the blood pressure is 121/78 mm Hg. A fine needle aspirate of the lymph node is sent for pathological investigation. Culture growth shows white colonies on Sabouraud glucose agar (SGA). Which of the following is the most likely causal organism?
AHistoplasma capsulatum
BMalassezia furfur
CBlastomyces dermatitidis
DCoccidioides immitis
EAspergillus fumigatus
A 52-year-old man comes to the physician because of a 4-day history of a productive cough, shortness of breath, and low-grade fever. He works as a farmer in southern Arizona. Physical examination shows multiple skin lesions with a dark blue center, pale intermediate zone, and red peripheral rim on the upper and lower extremities. There are diffuse crackles on the left side of the chest. An x-ray of the chest shows left basilar consolidation and left hilar lymphadenopathy. A photomicrograph of tissue obtained from a biopsy of the lung is shown. Which of the following is the most likely causal pathogen?
ACoccidioides immitis
BParacoccidioides brasiliensis
CCandida albicans
DBlastomyces dermatitidis
EAspergillus fumigatus
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