Chapter·MicrobiologyBiofilms

Biofilms in otitis media and sinusitisDownloads

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1

An 8-year-old boy with asthma is brought to the physician because of a 2-week history of facial pain and congestion. His mother states that the nasal discharge was initially clear, but it has become thicker and more purulent over the last week. He has tried multiple over-the-counter oral decongestants and antihistamines, with minimal relief. Current medications include cetirizine, intranasal oxymetazoline, and albuterol. His temperature is 37.7°C (99.8°F), pulse is 100/min, respirations are 14/min, and blood pressure is 110/70 mm Hg. Examination shows congested nasal mucosa with purulent discharge from the nares bilaterally. There is tenderness to palpation over the cheeks, with no transillumination over the maxillary sinuses. Which of the following is the most likely predisposing factor for this patient's current condition?

ANasal polyps

BViral upper respiratory tract infection

CRecent use of antihistamines

DForeign body

EAsthma

2

An investigator is studying the growth of an organism in different media. The organism is inoculated on a petri dish that contains heated sheep blood, vancomycin, nystatin, trimethoprim, and colistin. The resulting growth medium is incubated at 37°C. Numerous small, white colonies are seen after incubation for 48 hours. This organism is most likely to cause which of the following conditions?

APontiac fever

BPseudomembranous colitis

CHemolytic uremic syndrome

DOral thrush

EGonorrhea

3

An 8-year-old female presents to her pediatrician with nasal congestion. Her mother reports that the patient has had nasal congestion and nighttime cough for almost two weeks. The patient’s 3-year-old brother had similar symptoms that began around the same time and have since resolved. The patient initially seemed to be improving, but four days ago she began developing worsening nasal discharge and fever to 102.6°F (39.2°C) at home. Her mother denies any change in appetite. The patient denies sore throat, ear pain, and headache. She is otherwise healthy. In the office, her temperature is 102.2°F (39.0°C), blood pressure is 96/71 mmHg, pulse is 128/min, and respirations are 18/min. On physical exam, the nasal turbinates are edematous and erythematous. She has a dry cough. Purulent mucous can be visualized dripping from the posterior nasopharynx. Her maxillary sinuses are tender to palpation. Which of the following organisms is most likely to be causing this patient’s current condition?

AMoraxella catarrhalis

BStreptococcus pyogenes

CAdenovirus

DStreptococcus pneumoniae

EHaemophilus influenzae

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