Antithrombotic therapiesDownloads

An 11-year-old girl is brought to the emergency department after she fell during a dance class. She was unable to stand after the accident and has a painful and swollen knee. On presentation she says that she has had 2 previous swollen joints as well as profuse bleeding after minor cuts. Based on her presentation, a panel of bleeding tests is obtained with the following results: Bleeding time: 11 minutes Prothrombin time: 12 seconds Partial thromboplastin time: 52 seconds Which of the following treatments would be most effective in treating this patient's condition?

A 60-year-old woman presents to the emergency room with chest pain that started 20 minutes ago while watching television at home. The pain is substernal and squeezing in nature. She rates the pain as 6/10 and admits to having similar pain in the past with exertion. Her past medical history is significant for diabetes mellitus that is controlled with metformin. The physical examination is unremarkable. An electrocardiogram (ECG) shows ST-segment depression in the lateral leads. She is started on aspirin, nitroglycerin, metoprolol, unfractionated heparin, and insulin. She is asked not to take metformin while at the hospital. Three sets of cardiac enzymes are negative. Lab results are given below: Serum glucose 88 mg/dL Sodium 142 mEq/L Potassium 3.9 mEq/L Chloride 101 mEq/L Serum creatinine 1.2 mg/dL Blood urea nitrogen 22 mg/dL Cholesterol, total 170 mg/dL HDL-cholesterol 40 mg/dL LDL-cholesterol 80 mg/dL Triglycerides 170 mg/dL Hematocrit 38% Hemoglobin 13 g/dL Leucocyte count 7,500/mm3 Platelet count 185,000 /mm3 Activated partial thromboplastin time (aPTT) 30 seconds Prothrombin time (PT) 12 seconds Urinalysis Glucose negative Ketones negative Leucocytes negative Nitrites negative Red blood cells (RBC) negative Casts negative An echocardiogram reveals left ventricular wall motion abnormalities. With the pain subsiding, she was admitted and the medications were continued. A coronary angiography is planned in 4 days. In addition to regular blood glucose testing, which of the following should be closely monitored in this patient?