A 60-year-old woman presents to the clinic with a 3-month history of shortness of breath that worsens on exertion. She also complains of chronic cough that has lasted for 10 years. Her symptoms are worsened even with light activities like climbing up a flight of stairs. She denies any weight loss, lightheadedness, or fever. Her medical history is significant for hypertension, for which she takes amlodipine daily. She has a 70-pack-year history of cigarette smoking and drinks 3–4 alcoholic beverages per week. Her blood pressure today is 128/84 mm Hg. A chest X-ray shows flattening of the diaphragm bilaterally. Physical examination is notable for coarse wheezing bilaterally. Which of the following is likely to be seen with pulmonary function testing?
ADecreased FEV1: FVC and decreased total lung capacity
BNormal FEV1: FVC and decreased total lung capacity
CIncreased FEV1: FVC and decreased total lung capacity
DDecreased FEV1: FVC and increased total lung capacity
EIncreased FEV1: FVC and normal total lung capacity
Which of the following physiologic changes decreases pulmonary vascular resistance (PVR)?
AInhaling the inspiratory reserve volume (IRV)
BExhaling the entire vital capacity (VC)
CExhaling the expiratory reserve volume (ERV)
DBreath holding maneuver at functional residual capacity (FRC)
EInhaling the entire vital capacity (VC)
A 57-year-old man presents to the clinic for a chronic cough over the past 4 months. The patient reports a productive yellow/green cough that is worse at night. He denies any significant precipitating event prior to his symptoms. He denies fever, chest pain, palpitations, weight changes, or abdominal pain, but endorses some difficulty breathing that waxes and wanes. He denies alcohol usage but endorses a 35 pack-year smoking history. A physical examination demonstrates mild wheezes, bibasilar crackles, and mild clubbing of his fingertips. A pulmonary function test is subsequently ordered, and partial results are shown below: Tidal volume: 500 mL Residual volume: 1700 mL Expiratory reserve volume: 1500 mL Inspiratory reserve volume: 3000 mL What is the functional residual capacity of this patient?
A4500 mL
B2000 mL
C2200 mL
D3200 mL
E3500 mL
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