Chapter·BiostatisticsRCTs

Principles and design of RCTsDownloads

10Questions
9Flashcards
2Tables & Flowcharts

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Sample Questions

1

A 21-year-old man presents to the office for a follow-up visit. He was recently diagnosed with type 1 diabetes mellitus after being hospitalized for diabetic ketoacidosis following a respiratory infection. He is here today to discuss treatment options available for his condition. The doctor mentions a recent study in which researchers have developed a new version of the insulin pump that appears efficacious in type 1 diabetics. They are currently comparing it to insulin injection therapy. This new pump is not yet available, but it looks very promising. At what stage of clinical trials is this current treatment most likely at?

APhase 0

BPhase 2

CPhase 3

DPhase 1

EPhase 4

2

A pharmaceutical corporation has asked you to assist in the development of a randomized controlled trial (RCT) to evaluate the response of renal cell carcinoma to a novel chemotherapeutic agent. Despite all of the benefits that an RCT has to offer, which of the following would make an RCT unacceptable with regard to study design?

AProper treatment response is very common

BThe treatment is not widespread in use

CThe treatment does not represent the best known option

DThe treatment is expensive

EThe treatment has a known, adverse outcome

3

An investigator is measuring the blood calcium level in a sample of female cross country runners and a control group of sedentary females. If she would like to compare the means of the two groups, which statistical test should she use?

AChi-square test

BLinear regression

Ct-test

DANOVA (Analysis of Variance)

EF-test

+ 7 more in the PDF

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