Chapter·BiostatisticsP-values and confidence intervals

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1

A study is funded by the tobacco industry to examine the association between smoking and lung cancer. They design a study with a prospective cohort of 1,000 smokers between the ages of 20-30. The length of the study is five years. After the study period ends, they conclude that there is no relationship between smoking and lung cancer. Which of the following study features is the most likely reason for the failure of the study to note an association between tobacco use and cancer?

ALate-look bias

BLatency period

CConfounding

DEffect modification

EPygmalion effect

2

Group of 100 medical students took an end of the year exam. The mean score on the exam was 70%, with a standard deviation of 25%. The professor states that a student's score must be within the 95% confidence interval of the mean to pass the exam. Which of the following is the minimum score a student can have to pass the exam?

A45%

B63.75%

C67.5%

D20%

E65%

3

You are conducting a study comparing the efficacy of two different statin medications. Two groups are placed on different statin medications, statin A and statin B. Baseline LDL levels are drawn for each group and are subsequently measured every 3 months for 1 year. Average baseline LDL levels for each group were identical. The group receiving statin A exhibited an 11 mg/dL greater reduction in LDL in comparison to the statin B group. Your statistical analysis reports a p-value of 0.052. Which of the following best describes the meaning of this p-value?

AThere is a 95% chance that the difference in reduction of LDL observed reflects a real difference between the two groups

BThough A is more effective than B, there is a 5% chance the difference in reduction of LDL between the two groups is due to chance

CIf 100 permutations of this experiment were conducted, 5 of them would show similar results to those described above

DThis is a statistically significant result

EThere is a 5.2% chance of observing a difference in reduction of LDL of 11 mg/dL or greater even if the two medications have identical effects

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