A research group designed a study to investigate the epidemiology of syphilis in the United States. The investigators examined per capita income and rates of syphilis in New York City, Los Angeles, Chicago, and Houston. Data on city-wide syphilis rates was provided by each city's health agency. The investigators ultimately found that the number of new cases of syphilis was higher in low-income neighborhoods. This study is best described as which of the following?
ADouble-blind clinical trial
BProspective cohort study
CCase-control study
DCase series
EEcological study
A surgeon is interested in studying how different surgical techniques impact the healing of tendon injuries. In particular, he will compare 3 different types of suture repairs biomechanically in order to determine the maximum load before failure of the tendon 2 weeks after repair. He collects data on maximum load for 90 different repaired tendons from an animal model. Thirty tendons were repaired using each of the different suture techniques. Which of the following statistical measures is most appropriate for analyzing the results of this study?
AChi-squared
BWilcoxon rank sum
CPearson r coefficient
DStudent t-test
EANOVA
A 52-year-old man with stage IV melanoma comes to the physician with his wife for a routine follow-up examination. He was recently diagnosed with new bone and brain metastases despite receiving aggressive chemotherapy but has not disclosed this to his wife. He has given verbal consent to discuss his prognosis with his wife and asks the doctor to inform her of his condition because he does not wish to do so himself. She is tearful and has many questions about his condition. Which of the following would be the most appropriate statement by the physician to begin the interview with the patient's wife?
AHave you discussed a living will or goals of care together?
BWe should talk about how we can manage his symptoms with additional chemotherapy.
CWhy do you think your husband has not discussed his medical condition with you?
DWhat is your understanding of your husband's current condition?
EYour husband has end-stage cancer, and his prognosis is poor.
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