Chapter·Behavioral ScienceEthics/Biostatistics

Effect size and clinical significanceDownloads

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1

A randomized double-blind controlled trial is conducted on the efficacy of 2 different ACE-inhibitors. The null hypothesis is that both drugs will be equivalent in their blood-pressure-lowering abilities. The study concluded, however, that Medication 1 was more efficacious in lowering blood pressure than medication 2 as determined by a p-value < 0.01 (with significance defined as p ≤ 0.05). Which of the following statements is correct?

AWe can accept the null hypothesis.

BWe can reject the null hypothesis.

CThis trial did not reach statistical significance.

DThere is a 0.1% chance that medication 2 is superior.

EThere is a 10% chance that medication 1 is superior.

2

A study is performed to determine the prevalence of a particular rare fungal pneumonia. A sample population of 100 subjects is monitored for 4 months. Every month, the entire population is screened and the number of new cases is recorded for the group. The data from the study are given in the table below: Time point New cases of fungal pneumonia t = 0 months 10 t = 1 months 4 t = 2 months 2 t = 3 months 5 t = 4 months 4 Which of the following is correct regarding the prevalence of this rare fungal pneumonia in this sample population?

AThe prevalence at time point 2 months is 2%.

BThe prevalence at time point 3 months is 11%.

CThe prevalence at the conclusion of the study is 15%.

DThe prevalence and the incidence at time point 2 months are equal.

EThe prevalence at the conclusion of the study is 25%.

3

Group of 100 medical students took an end of the year exam. The mean score on the exam was 70%, with a standard deviation of 25%. The professor states that a student's score must be within the 95% confidence interval of the mean to pass the exam. Which of the following is the minimum score a student can have to pass the exam?

A45%

B63.75%

C67.5%

D20%

E65%

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