A 34-year-old patient presents with severe pain in the right upper quadrant that radiates to the right shoulder. During laparoscopic cholecystectomy, which of the following anatomical spaces must be carefully identified to prevent bile duct injury?
AForamen of Winslow
BLesser sac
CCalot's triangle
DMorrison's pouch
A 45-year-old man comes to the physician for a routine health maintenance examination. He feels well. He has type 2 diabetes mellitus. There is no family history of serious illness. He works as an engineer at a local company. He does not smoke. He drinks one glass of red wine every other day. He does not use illicit drugs. His only medication is metformin. He is 180 cm (5 ft 11 in) tall and weighs 100 kg (220 lb); BMI is 31 kg/m2. His vital signs are within normal limits. Examination shows a soft, nontender abdomen. The liver is palpated 2 to 3 cm below the right costal margin. Laboratory studies show an aspartate aminotransferase concentration of 100 U/L and an alanine aminotransferase concentration of 130 U/L. Liver biopsy shows hepatocyte ballooning degeneration, as well as inflammatory infiltrates with scattered lymphocytes, neutrophils, and Kupffer cells. Which of the following is the most likely diagnosis?
ANonalcoholic steatohepatitis
BAutoimmune hepatitis
CViral hepatitis
DPrimary biliary cholangitis
EAlcoholic fatty liver disease
A 57-year-old man presents with fever and yellow discoloration of the skin for the past 4 days. He denies any recent weight loss or changes in urine or stool color. His past medical history is unremarkable. He admits to drinking about 130 g/day of alcohol and says he has been doing so for the past 25 years. His wife who is accompanying him during this visit adds that once her husband drank 15 cans of beer at a funeral. The patient also reports a 10-pack-year smoking history. His vital signs include: pulse 98/min, respiratory rate 13/min, temperature 38.2°C (100.8°F) and blood pressure 120/90 mm Hg. On physical examination, the patient appears jaundiced and is ill-appearing. Sclera is icteric. Abdominal examination reveals tenderness to palpation in the right upper quadrant with no rebound or guarding. Percussion reveals significant hepatomegaly extending 3 cm below the right costal margin. Laboratory studies are significant for the following: Sodium 135 mEq/L Potassium 3.5 mEq/L ALT 240 U/L AST 500 U/L A liver biopsy is obtained but the results are pending. Which of the following would most likely be seen in this patient's biopsy?
ASteatosis alone
BHürthle cells
C'Florid' bile duct lesion
DGaucher cells
EMallory-Denk bodies
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