A 28-year-old woman and her husband are admitted to the office due to difficulties conceiving a child for the past year. Her menarche was at the age of 15 years, and her periods have been regular since then. Her medical history is positive for an abortion with curettage 5 years ago. A spermogram on the partner is performed, and it shows motile sperm cells. An ultrasound is performed on the patient and it is unremarkable. The laboratory results show that the FSH, LH, TSH, and prolactin levels are within normal ranges. A hysteroscopy is additionally performed and multiple adhesions are found in the uterus (refer to the image). Which of the following is the most likely composition of the scar tissue present in the uterus?
AType 3 collagen
BType 4 collagen
CType 2 collagen
DType 1 collagen
EElastin
A 7-year-old girl presents to her primary care physician for a routine check-up. The physician allows the medical student to perform a physical examination. The medical student notes hearing impairment as well as the findings show in Figures A and B. Radiographs show indications of multiple old fractures of the humerus that have healed. After questioning the girl’s parents, the medical student learns that in addition, the patient is extremely picky with her food and eats a diet consisting mainly of cereal and pasta. What is the most likely etiology of the patient’s disease?
ADietary deficiency of ascorbic acid
BDefect in type I collagen
CDefective mineralization of cartilage
DDecreased bone mineral density
ENon-accidental trauma
An epidemiologist is evaluating the efficacy of Noxbinle in preventing HCC deaths at the population level. A clinical trial shows that over 5 years, the mortality rate from HCC was 25% in the control group and 15% in patients treated with Noxbinle 100 mg daily. Based on this data, how many patients need to be treated with Noxbinle 100 mg to prevent, on average, one death from HCC?
A20
B73
C10
D50
E100
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