A 50-year-old male is brought to the dermatologist's office with complaints of a pigmented lesion. The lesion is uniformly dark with clean borders and no asymmetry and has been increasing in size over the past two weeks. He works in construction and spends large portions of his day outside. The dermatologist believes that this mole should be biopsied. To prepare the patient for the biopsy, the dermatologist injects a small amount of lidocaine into the skin around the lesion. Which of the following nerve functions would be the last to be blocked by the lidocaine?
APain
BTouch
CTemperature
DSympathetic stimulation
EPressure
A 59-year-old woman presents to the emergency room with severe low back pain. She reports pain radiating down her left leg into her left foot. She also reports intermittent severe lower back spasms. The pain started after lifting multiple heavy boxes at her work as a grocery store clerk. She denies bowel or bladder dysfunction. Her past medical history is notable for osteoporosis and endometrial cancer. She underwent a hysterectomy 20 years earlier. She takes alendronate. Her temperature is 99°F (37.2°C), blood pressure is 135/85 mmHg, pulse is 85/min, and respirations are 22/min. Her BMI is 21 kg/m^2. On exam, she is unable to bend over due to pain. Her movements are slowed to prevent exacerbating her muscle spasms. A straight leg raise elicits severe radiating pain into her left lower extremity. The patient reports that the pain is worst along the posterior thigh and posterolateral leg into the fourth and fifth toes. Palpation along the lumbar vertebral spines demonstrates mild tenderness. Patellar reflexes are 2+ bilaterally. The Achilles reflex is decreased on the left. Which nerve root is most likely affected in this patient?
AL5
BS2
CL3
DL4
ES1
A 27-year-old woman develops progressive difficulty breathing after a long day of chores in a dusty house. These chores included brushing the family dog, vacuuming, dusting, and sweeping. She occasionally gets these episodes once or twice a year and has her medication on hand. Her symptoms are reversed by inhaling a β2-adrenergic receptor agonist. Which of the following chemical mediators is responsible for this patient’s breathing difficulties?
AHistamine
BLeukotrienes
CSerotonin
DBradykinin
EEndorphins
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