Two hours after admission to the intensive care unit, a 56-year-old man with necrotizing pancreatitis develops profound hypotension. His blood pressure is 80/50 mm Hg and he is started on vasopressors. A central venous access line is placed. Which of the following is most likely to decrease the risk of complications from this procedure?
APlacement of the central venous line in the femoral vein
BReplacement of the central venous line every 7-10 days
CInitiation of anticoagulation after placement
DPreparation of the skin with chlorhexidine and alcohol
EInitiation of periprocedural systemic antibiotic prophylaxis
A 60-year-old female presents to her primary care physician complaining of bloating and fatigue over the past year. On examination, she has abdominal distension and ascites. Abdominal imaging reveals a mass-like lesion affecting the left ovary. A biopsy of the lesion demonstrates serous cystadenocarcinoma. She is subsequently started on a chemotherapeutic medication known to stabilize polymerized microtubules. Which of the following complications should this patient be monitored for following initiation of this medication?
APeripheral neuropathy
BPulmonary fibrosis
CAcoustic nerve damage
DHemorrhagic cystitis
ECardiotoxicity
A 30-year-old man comes to the physician for a follow-up examination 1 month after sustaining a chemical burn over the dorsum of his right hand and forearm. Physical examination shows hyperextension of the hand at the wrist. The skin over the dorsum of the wrist is tense and there is a thick, epithelialized scar. Range of motion of the right wrist is restricted. This patient's contracture is most likely due to activity of which of the following cells?
AFibroblasts
BMyofibroblasts
CNeutrophils
DMacrophages
EEndothelial cells
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