A 40-year-old female volunteers for an invasive study to measure her cardiac function. She has no previous cardiovascular history and takes no medications. With the test subject at rest, the following data is collected using blood tests, intravascular probes, and a closed rebreathing circuit: Blood hemoglobin concentration 14 g/dL Arterial oxygen content 0.22 mL O2/mL Arterial oxygen saturation 98% Venous oxygen content 0.17 mL O2/mL Venous oxygen saturation 78% Oxygen consumption 250 mL/min The patient's pulse is 75/min, respiratory rate is 14/ min, and blood pressure is 125/70 mm Hg. What is the cardiac output of this volunteer?
ABody surface area is required to calculate cardiac output.
BStroke volume is required to calculate cardiac output.
C250 mL/min
D5.0 L/min
E50 L/min
A 50-year-old woman comes to the physician for a routine health maintenance examination. She has no personal or family history of serious illness. She smoked one pack of cigarettes daily for 5 years during her 20s. Her pulse is 70/min, and blood pressure is 120/78 mm Hg. Serum lipid studies and glucose concentration are within the reference ranges. Which of the following health maintenance recommendations is most appropriate at this time?
APerform BRCA gene test
BPerform abdominal ultrasound
CPerform 24-hour ECG
DPerform DEXA scan
EPerform colonoscopy
An epidemiologist is evaluating the efficacy of Noxbinle in preventing HCC deaths at the population level. A clinical trial shows that over 5 years, the mortality rate from HCC was 25% in the control group and 15% in patients treated with Noxbinle 100 mg daily. Based on this data, how many patients need to be treated with Noxbinle 100 mg to prevent, on average, one death from HCC?
A20
B73
C10
D50
E100
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