A 30-year-old man comes to the physician for follow-up evaluation for hypertension. He reports a 1-month history of episodic throbbing headaches, palpitations, and paroxysmal sweating. Blood pressure is 160/90 mm Hg. He appears pale but physical examination is otherwise unremarkable. Laboratory studies show elevated urine and plasma metanephrines. A CT scan of the abdomen shows a mass in the left adrenal gland. Which of the following is the most appropriate initial pharmacotherapy for this patient?
APropranolol
BPhenoxybenzamine
CHydrochlorothiazide
DOctreotide
EClonidine
A 25-year-old man presents to the emergency department with a severe pulsatile headache for an hour. He says that he is having palpitations as well. He adds that he has had several episodes of headache in the past which resolved without seeking medical attention. He is a non-smoker and does not drink alcohol. He denies use of any illicit drugs. He looks scared and anxious. His temperature is 37°C (98.6°F), respirations are 25/min, pulse is 107/min, and blood pressure is 221/161 mm Hg. An urgent urinalysis reveals elevated plasma metanephrines. What is the next best step in the management of this patient?
AHydralazine
BAmlodipine
CPhenoxybenzamine followed by propranolol
DPropranolol followed by phenoxybenzamine
EEmergent surgery
A 20-year-old man is brought to the emergency room for evaluation of a back injury sustained while at work. A CT scan of the lumbar spine shows an incidental 2-cm mass adjacent to the inferior vena cava. Histologic examination of a biopsy specimen of the mass shows clusters of chromaffin cells. This mass is most likely to secrete which of the following substances?
AAldosterone
BDehydroepiandrosterone
CNorepinephrine
DCortisol
EEstrogen
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