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Nipple discharge evaluationDownloads

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1

A 33-year-old woman presents to her primary care physician for non-bloody nipple discharge. She states that it has been going on for the past month and that it sometimes soils her shirt. The patient drinks 2 to 3 alcoholic beverages per day and smokes 1 pack of cigarettes per day. She is currently seeking mental health treatment with an outpatient psychiatrist after a recent hospitalization for auditory hallucinations. Her psychiatrist prescribed her a medication that she can not recall. Otherwise, she complains of headaches that occur frequently. Her temperature is 98.6°F (37.0°C), blood pressure is 137/68 mmHg, pulse is 70/min, respirations are 13/min, and oxygen saturation is 98% on room air. Physical exam is notable for bilateral galactorrhea that can be expressed with palpation. Which of the following is the best next step in management?

AUltrasound and biopsy

BMammography

CSerum prolactin level

DCT scan of the head

EDiscontinuation of current psychiatric medications

2

A 37-year-old woman presents to her primary care physician for bilateral nipple discharge. The patient states that she has observed a milky discharge coming from her nipples for the past month. On review of systems, the patient states that she has felt fatigued lately and has experienced decreased libido. She also endorses headaches that typically resolve by the middle of the day and a 5 pound weight gain this past month. The patient has a past medical history of obesity, schizophrenia, and constipation. Her temperature is 99.5°F (37.5°C), blood pressure is 145/95 mmHg, pulse is 60/min, respirations are 15/min, and oxygen saturation is 98% on room air. On physical exam, you note an obese, fatigued-appearing woman. Dermatologic exam reveals fine, thin hair over her body. Cardiopulmonary exam is within normal limits. Neurological exam reveals cranial nerves II-XII as grossly intact. The patient exhibits 1+ sluggish reflexes. Which of the following is the most likely diagnosis?

ADopamine blockade in the tuberoinfundibular pathway

BProtein-secreting CNS mass

CNormal pregnancy

DViral infection of the thyroid gland

EAutoimmune destruction of the thyroid gland

3

A 29-year-old nulligravid woman comes to the physician because of a 10-day history of small quantities of intermittent, blood-tinged discharge from her left nipple. There is no personal or family history of serious illness. She has smoked 1 pack of cigarettes daily for 5 years. Her last menstrual period was 12 days ago. She is sexually active and uses condoms inconsistently. Physical examination shows scant serosanguinous fluid expressible from the left nipple. There is no palpable breast mass or axillary lymphadenopathy. Examination shows no other abnormalities. Which of the following is the most appropriate next step in management?

AImage-guided core biopsy of the affected duct

BSubareolar ultrasound

CNipple discharge cytology

DReassurance

EBreast MRI

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