Chapter·PhysiologyCardiac cycle

Pressure-volume relationshipsDownloads

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1

A 40-year-old female volunteers for an invasive study to measure her cardiac function. She has no previous cardiovascular history and takes no medications. With the test subject at rest, the following data is collected using blood tests, intravascular probes, and a closed rebreathing circuit: Blood hemoglobin concentration 14 g/dL Arterial oxygen content 0.22 mL O2/mL Arterial oxygen saturation 98% Venous oxygen content 0.17 mL O2/mL Venous oxygen saturation 78% Oxygen consumption 250 mL/min The patient's pulse is 75/min, respiratory rate is 14/ min, and blood pressure is 125/70 mm Hg. What is the cardiac output of this volunteer?

ABody surface area is required to calculate cardiac output.

BStroke volume is required to calculate cardiac output.

C250 mL/min

D5.0 L/min

E50 L/min

2

A 76-year-old male with a history of chronic uncontrolled hypertension presents to the emergency room following an episode of syncope. He reports that he felt lightheaded and experienced chest pain while walking his dog earlier in the morning. He notes that he has experienced multiple similar episodes over the past year. A trans-esophageal echocardiogram demonstrates a thickened, calcified aortic valve with left ventricular hypertrophy. Which of the following heart sounds would likely be heard on auscultation of this patient?

ACrescendo-decrescendo murmur radiating to the carotids that is loudest at the right upper sternal border

BDiastolic rumble following an opening snap with an accentuated S1

CEarly diastolic high-pitched blowing decrescendo murmur that is loudest at the left sternal border

DHolosystolic murmur radiating to the axilla that is loudest at the apex

EMidsystolic click that is loudest at the apex

3

A 37-year-old man is brought to the emergency department by ambulance after a motor vehicle accident. He suffered multiple deep lacerations and experienced significant blood loss during transport. In the emergency department, his temperature is 98.6°F (37°C), blood pressure is 102/68 mmHg, pulse is 112/min, and respirations are 22/min. His lacerations are sutured and he is given 2 liters of saline by large bore intravenous lines. Which of the following changes will occur in this patient's cardiac physiology due to this intervention?

AIncreased cardiac output and unchanged right atrial pressure

BDecreased cardiac output and increased right atrial pressure

CIncreased cardiac output and decreased right atrial pressure

DIncreased cardiac output and increased right atrial pressure

EDecreased cardiac output and decreased right atrial pressure

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