A newborn infant is born at 40 weeks gestation to a G1P1 mother. The pregnancy was uncomplicated and was followed by the patient's primary care physician. The mother has no past medical history and is currently taking a multi-vitamin, folate, B12, and iron. The infant is moving its limbs spontaneously and is crying. His temperature is 98.7°F (37.1°C), blood pressure is 60/38 mmHg, pulse is 150/min, respirations are 33/min, and oxygen saturation is 99% on room air. Which of the following is the best next step in management?
ANo further management needed
BIntramuscular (IM) vitamin K and topical erythromycin
CFluid resuscitation
DVitamin D and IM vitamin K
ESilver nitrate eye drops and basic lab work
A neonate born at 33 weeks is transferred to the NICU after a complicated pregnancy and C-section. A week after being admitted, he developed a fever and became lethargic and minimally responsive to stimuli. A lumbar puncture is performed that reveals the following: Appearance Cloudy Protein 64 mg/dL Glucose 22 mg/dL Pressure 330 mm H20 Cells 295 cells/mm³ (> 90% PMN) A specimen is sent to microbiology and reveals gram-negative rods. Which of the following is the next appropriate step in management?
AMRI scan of the head
BStart the patient on IV ceftriaxone
CProvide supportive measures only
DStart the patient on IV cefotaxime
EStart the patient on oral rifampin
Five days after being admitted to the hospital for a scald wound, a 2-year-old boy is found to have a temperature of 40.2°C (104.4°F). He does not have difficulty breathing, cough, or painful urination. He initially presented one hour after spilling a pot of boiling water on his torso while his mother was cooking dinner. He was admitted for fluid resuscitation, nutritional support, pain management, and wound care, and he was progressing well until today. He has no other medical conditions. Other than analgesia during this hospital stay, he does not take any medications. He appears uncomfortable but not in acute distress. His pulse is 150/min, respirations are 41/min, and blood pressure is 90/50 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 99%. Examination shows uneven, asymmetrical scalding covering his anterior torso in arrow-like patterns with surrounding erythema and purulent discharge. The remainder of the examination shows no abnormalities. His hemoglobin is 13.4 g/dL, platelet count is 200,000/mm3, and leukocyte count is 13,900/mm3. Which of the following is the most appropriate initial pharmacological treatment for this patient?
AVancomycin and metronidazole
BAmoxicillin/clavulanic acid and ceftriaxone
CAmpicillin/sulbactam and daptomycin
DVancomycin and cefepime
EPiperacillin/tazobactam and cefepime
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