A 3-year-old boy presents to the clinic for evaluation of leg pain. This has been persistent for the past 3 days and accompanied by difficulty walking. He has also had some erythema and ecchymoses in the periorbital region over the same time period. The vital signs are unremarkable. The physical exam notes the above findings, as well as some swelling of the upper part of the abdomen. The laboratory results are as follows: Erythrocyte count 3.3 million/mm3 Leukocyte count 3,000/mm3 Neutrophils 54% Eosinophils 1% Basophils 1% Lymphocytes 43% Monocytes 3% Platelet count 80,000/mm3 A magnetic resonance image (MRI) scan of the abdomen shows a mass of adrenal origin. Which of the following is the most likely cause of this patient's symptoms?
AHepatoblastoma
BRhabdomyosarcoma
CNeuroblastoma
DWilms tumor
ERetinoblastoma
A 1-year-old boy is brought to the physician for a well-child examination. He has no history of serious illness. His older sister had an eye disease that required removal of one eye at the age of 3 years. Examination shows inward deviation of the right eye. Indirect ophthalmoscopy shows a white reflex in the right eye and a red reflex in the left eye. The patient is at increased risk for which of the following conditions?
AGastric cancer
BNeuroblastoma
CWilms tumor
DBasal cell carcinoma
EOsteosarcoma
A 3-year-old girl is brought to the physician by her parents due to observations of rapid, random, horizontal and vertical eye movements along with occasional jerking movements of her limbs and head. CT scan reveals an abdominal mass that crosses the midline. Further work-up reveals elevated 24-hour urinary homovanillic acid and vanillylmandelic acid. Neuroblastoma is suspected. Which of the following diseases pathologically originates from the same type of cells as Neuroblastoma?
APilocytic astrocytoma
BCraniopharyngioma
CMedulloblastoma
DHirschsprung disease
ERetinoblastoma
+ 7 more in the PDF
Browse all chapters