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1

A 45-year-old male reports several years of asbestos exposure while working in the construction industry. He reports smoking 2 packs of cigarettes per day for over 20 years. Smoking and asbestos exposure increase the incidence of which of the following diseases?

AEmphysema

BMalignant pulmonary mesothelioma

CMultiple myeloma

DBronchogenic carcinoma

EChronic bronchitis

2

A 44-year-old man is brought to the emergency department after sustaining high-voltage electrical burns over his left upper limb. On examination, the tip of his left middle finger is charred, and there are 2nd-degree burns involving the whole of the left upper limb. Radial and ulnar pulses are strong, and there are no signs of compartment syndrome. An exit wound is present over the sole of his right foot. His temperature is 37.7°C (99.8°F), the blood pressure is 110/70 mm Hg, the pulse is 105/min, and the respiratory rate is 26/min. His urine is reddish-brown, and urine output is 0.3 mL/kg/h. Laboratory studies show: Hemoglobin 13.9 g/dL Hematocrit 33% Leukocyte count 11,111/mm3 Serum Creatinine 4.6 mg/dL Creatine phosphokinase 15,230 U/L K+ 7.7 mEq/L Na+ 143 mEq/L What is the most likely mechanism for this patient's renal failure?

ASepticemia leading to acute pyelonephritis

BRhabdomyolysis, myoglobinuria, and renal injury

CDirect visceral electrical injury to the kidneys

DFluid and electrolyte loss and hypovolemia

EVolume overload because of excessive intravenous fluid resuscitation

3

A neonate suffering from neonatal respiratory distress syndrome is given supplemental oxygen. Which of the following is a possible consequence of oxygen therapy in this patient?

AAnosmia

BAtelectasis

CAtopy

DBlindness

ECardiac anomalies

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