Chapter·PathologyCell injury

Ischemia-reperfusion injuryDownloads

10Questions
10Flashcards
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Sample Questions

1

An 82-year-old woman is brought to the emergency department after losing consciousness at her nursing home. She had been watching TV for several hours and while getting up to use the bathroom, she fell and was unconscious for several seconds. She felt dizzy shortly before the fall. She does not have a headache or any other pain. She has a history of hypertension, intermittent atrial fibrillation, and stable angina pectoris. Current medications include warfarin, aspirin, hydrochlorothiazide, and a nitroglycerin spray as needed. Her temperature is 36.7°C (98.1°F), pulse is 100/min and regular, and blood pressure is 102/56 mm Hg. Physical exam shows a dry tongue. A fold of skin that is pinched on the back of her hand unfolds after 2 seconds. Cardiopulmonary examination shows no abnormalities. Further evaluation of this patient is most likely to show which of the following findings?

AElevated serum concentration of cardiac enzymes

BElevated serum creatine kinase concentration

CAbsent P waves on ECG

DElevated blood urea nitrogen concentration

EHypodense lesions on CT scan of the head

2

A 23-year-old woman is brought to the emergency department 30 minutes after stepping on a piece of broken glass. Physical examination shows a 3-cm, ragged laceration on the plantar aspect of the left foot. The physician uses hydrogen peroxide to clean the wound. Which of the following is the most likely mechanism of action of this disinfectant?

AFormation of free radicals

BIntercalation of DNA

CCrosslinking of proteins

DHalogenation of nucleic acids

ECongealing of cytoplasm

3

What is the primary mechanism for maintaining constant cerebral blood flow despite changes in systemic blood pressure?

AEndothelial factors

BBaroreceptor reflex

CMyogenic autoregulation

DMetabolic control

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