Chapter·MicrobiologyViruses

Gastroenteritis viruses (norovirus, rotavirus)Downloads

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1

A 3-year-old boy is brought to the pediatrician by his parents with a presentation of severe diarrhea, vomiting, and fever for the past 2 days. The child is enrolled at a daycare where several other children have had similar symptoms in the past week. On physical exam, the child is noted to have dry mucous membranes. His temperature is 102°F (39°C). Questions regarding previous medical history reveal that the child’s parents pursued vaccine exemption to opt out of most routine vaccinations for their child. The RNA virus that is most likely causing this child’s condition has which of the following structural features?

ASingle-stranded, icosahedral, non-enveloped

BDouble-stranded, icosahedral, non-enveloped

CSingle-stranded, helical, enveloped

DSingle-stranded, icosahedral, enveloped

EDouble-stranded, helical, non-enveloped

2

A 7-year-old boy is brought to the emergency room because of severe, acute diarrhea. He is drowsy with a dull, lethargic appearance. He has sunken eyes, poor skin turgor, and dry oral mucous membranes and tongue. He has a rapid, thready pulse with a systolic blood pressure of 60 mm Hg and his respirations are 33/min. His capillary refill time is 6 sec. He has had no urine output for the past 24 hours. Which of the following is the most appropriate next step in treatment?

AStart IV fluid resuscitation by administering colloid solutions

BProvide oral rehydration therapy to correct dehydration

CGive initial IV bolus of 2 L of Ringer’s lactate, followed by packed red cells, fresh frozen plasma, and platelets in a ratio of 1:1:1

DStart IV fluid resuscitation with normal saline or Ringer’s lactate, along with monitoring of vitals and urine output

EGive antidiarrheal drugs

3

A 55-year-old man presents to the emergency department with nausea and vomiting. The patient states that he has felt nauseous for the past week and began vomiting last night. He thought his symptoms would resolve but decided to come in when his symptoms worsened. He feels that his symptoms are exacerbated with large fatty meals and when he drinks alcohol. His wife recently returned from a cruise with symptoms of vomiting and diarrhea. The patient has a past medical history of poorly managed diabetes, constipation, anxiety, dyslipidemia, and hypertension. His temperature is 99.5°F (37.5°C), blood pressure is 197/128 mmHg, pulse is 100/min, respirations are 17/min, and oxygen saturation is 95% on room air. Physical exam reveals a systolic murmur heard loudest along the left upper sternal border. Abdominal exam reveals an obese, tympanitic and distended abdomen with a 3 cm scar in the right lower quadrant. Vascular exam reveals weak pulses in the lower extremities. Which of the following is the most likely diagnosis?

AEnteric nervous system damage

BTwisting of the bowel

CAdhesions

DNorovirus

EImpacted stool

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