A 34-year-old man comes to the physician because of progressive swelling of the left lower leg for 4 months. One year ago, he had an episode of intermittent fever and tender lymphadenopathy that occurred shortly after he returned from a trip to India and resolved spontaneously. Physical examination shows 4+ nonpitting edema of the left lower leg. His leukocyte count is 8,000/mm3 with 25% eosinophils. A blood smear obtained at night confirms the diagnosis. Treatment with diethylcarbamazine is initiated. Which of the following is the most likely route of transmission of the causal pathogen?
APenetration of the skin by hookworms in feces
BPenetration of the skin by cercariae from contaminated fresh water
CDeposition of larvae into the skin by a female black fly
DIngestion of encysted larvae in undercooked pork
EDeposition of thread-like larvae into the skin by a female mosquito
A 7-year-old girl is brought to the physician by her mother because of a 4-week history of irritability, diarrhea, and a 2.2-kg (5-lb) weight loss that was preceded by a dry cough. The family returned from a vacation to Indonesia 2 months ago. Her vital signs are within normal limits. Abdominal examination shows mild tenderness with no guarding or rebound and increased bowel sounds. Her leukocyte count is 9,200/mm3 with 20% eosinophils. A photomicrograph of a wet stool mount is shown. Which of the following is the most appropriate pharmacotherapy?
ADiethylcarbamazine
BMetronidazole
CAlbendazole
DPraziquantel
EDoxycycline
A 19-year-old woman presents to the emergency department with chronic diarrhea, fatigue, and weakness. She also had mild lower extremity edema. On examination, she was noted to be pale. Blood testing revealed peripheral eosinophilia (60%) and a Hb concentration of 8 g/dL. The stool examination revealed Fasciolopsis buski eggs. Which of the following drugs would most likely be effective?
AAlbendazole
BOxamniquine
CNiclosamide
DPraziquantel
EBithionol
+ 7 more in the PDF
Browse all chapters