A 29-year-old woman, gravida 1, para 0, at 33 weeks' gestation comes to her doctor for a routine visit. Her pregnancy has been uncomplicated. She has systemic lupus erythematosus and has had no flares during her pregnancy. She does not smoke cigarettes, drink alcohol, or use illicit drugs. Current medications include iron, vitamin supplements, and hydroxychloroquine. Her temperature is 37.2°C (98.9°F), pulse is 70/min, respirations are 17/min, and blood pressure is 134/70 mm Hg. She appears well. Physical examination shows no abnormalities. Ultrasound demonstrates fetal rhythmic breathing for > 30 seconds, amniotic fluid with deepest vertical pocket of 1 cm, one distinct fetal body movement over 30 minutes, and no episodes of extremity extension over 30 minutes. Nonstress test is reactive and reassuring. Which of the following is the next best step in management?
AAdminister corticosteroids and continue close monitoring
BPerform cesarean delivery
CDiscontinue hydroxychloroquine and continue close monitoring
DInduction of labor
EReassurance with expectant management
A 40-year-old man presents to a clinic in Michigan in December complaining of painful blue fingers and toes. He also complains of numbness and tingling. The patient’s vital signs are within normal limits, and his symptoms typically disappear when he comes back into a warm room. The patient also notes that he recently moved to the area from Arizona and had recently recovered from a viral infection in which he had a low-grade fever and severe lymphadenopathy. Which of the following tests would most likely be positive in this patient?
ADirect Coomb’s test with anti-C3 reagent
BAnti-centromere antibody
CAnti-Ro antibody
DIndirect Coomb’s test
EDirect Coomb’s test with anti-IgG reagent
A 29-year-old woman presents to the emergency department with joint pain and a notable rash. She has had joint pain for the past 12 months but noticed the rash recently as well as generalized malaise. She states her joint pain is symmetric, in her upper extremities, and is worse in the morning. Her temperature is 97.6°F (36.4°C), blood pressure is 111/74 mmHg, pulse is 83/min, respirations are 14/min, and oxygen saturation is 98% on room air. Laboratory studies are ordered as seen below. Hemoglobin: 10 g/dL Hematocrit: 30% Leukocyte count: 6,800/mm^3 with normal differential Platelet count: 207,000/mm^3 Serum: Na+: 140 mEq/L Cl-: 101 mEq/L K+: 4.9 mEq/L HCO3-: 21 mEq/L BUN: 30 mg/dL Glucose: 120 mg/dL Creatinine: 1.8 mg/dL The patient is ultimately admitted to the hospital. Which of the following is the most appropriate test to monitor her disease progression?
ARheumatoid factor
BAnti-topoisomerase
CAnti-dsDNA
DAnti-CCP
EAnti-nuclear antibody
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