For which of the following patients would you recommend prophylaxis against mycobacterium avium-intracellulare?
A30-year old HIV positive male with CD4 count of 20 cells/microliter and a viral load of < 50 copies/mL
B22-year old HIV positive female with CD4 count of 750 cells/microliter and a viral load of 500,000 copies/mL
C45-year old HIV positive female with CD4 count of 250 cells/microliter and a viral load of 100,000 copies/mL
D50-year old HIV positive female with CD4 count of 150 cells/microliter and a viral load of < 50 copies/mL
E36-year old HIV positive male with CD4 count of 75 cells/microliter and an undetectable viral load
A 60-year-old man comes to the physician’s office with jaundice. Liver ultrasound reveals a shrunken liver and biopsy reveals cirrhosis. Hepatitis serologies are below: Anti-HAV: negative HBsAg: negative HBsAb: positive HBeAg: negative Anti-HBe: negative Anti-HBc: negative Anti-HCV: positive The hepatitis C viral load is 1,000,000 copies/mL. The patient is started on an antiviral regimen including sofosbuvir. What is the mechanism of action of this drug?
AInhibits reverse transcriptase
BInhibits integrase
CInhibits synthesis of DNA-dependent DNA polymerase
DInhibits RNA-dependent RNA polymerase
EInhibits hepatitis C protease
A 33-year-old HIV-positive male is seen in clinic for follow-up care. When asked if he has been adhering to his HIV medications, the patient exclaims that he has been depressed, thus causing him to not take his medication for six months. His CD4+ count is now 33 cells/mm3. What medication(s) should he take in addition to his anti-retroviral therapy?
AAzithromycin and fluconazole
BAzithromycin, dapsone, and fluconazole
CDapsone
DFluconazole
EAzithromycin and trimethoprim-sulfamethoxazole
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